Wednesday, September 25, 2019

Herbalogy or Entomology ? Medicinal Uses of Insects



https://www.newdelhitimes.com/value-of-insects-in-medical-science/

Value of Insects in Medical Science





By Smt. Maneka Sanjay Gandhi






There are no pests, no weeds, in nature. There are beings who get in the way of humans growing food, or destroying the habitat in order to take up residence and make service
centres for these human populations. Billions of insects are killed by pesticides alone for
this purpose.
Human beings have used insects as medicine in different human cultures throughout the
world, but very little research was done to convert local use into proven, standardized
medicine. Entomotherapy is a branch of science that uses insects for medicine. The rise of antibiotic resistant infections has forced pharmaceutical research into looking for new resources. Many insects, used in alternative medicine, are now being tested for mainstream medical products. FDA, for instance, recently approved the flu vaccine, Flublok, which is derived from cells taken from the ovaries of the fall armyworm moth.
One insect alone, the honey bee, provides honey, pollen, royal jelly, propolis and an anti-inflammatory peptide melittin. Honey is applied to skin to treat scar tissue, rashes and burns, and as an eye poultice, for digestive problems and as a general health restorative. It is taken
hot to treat colds, coughs, laryngitis, tuberculosis, throat infections and lung diseases.
Apitoxin (honey bee venom) is applied through direct stings to relieve arthritis, rheumatism, polyneuritis and asthma. Propolis, used by bees as a hive insulator and sealant, is said to
sw hbnhave antibiotic, anaesthetic, and anti-inflammatory properties. Royal jelly is used to
treat anaemia, ulcers, arteriosclerosis and hypertension. Bee pollen is eaten as a health restorative.
Over a thousand protein families have been identified in the saliva of blood-feeding insects; these may provide useful drugs such as anticoagulants, vasodilators, antihistamines and anaesthetics.
Here are some lesser known insects who are used in human medicine :
1. The University of Miami is researching the use of the venom of the South American
Devil Tree Ant in rheumatoid arthritis. Half the patients were injected with venom extract.
The other half with placebos. Those who received the venom derivative showed dramatic reduction in the number and intensity of inflamed joints, and marked increases in their
freedom of motion. Patients who received the placebo showed no improvement. A U.S.
patent is pending on the chemical.
Many native healers use ants. Black Mountain Ant extracts dilate blood vessels that supply
the penis. The venom of the Red Harvester Ant was used to cure rheumatism, arthritis and poliomyelitis. The South American tree ant, Pseudomyrmex sp., commonly called as the Samsum Ant’s venom can reduce inflammation, inhibit tumour growth and treat liver
ailments.
Even 3,000 years ago the mandibles of soldier ants were used as stitches. The ant was
agitated, and when it opened its jaws , it was placed around the wound to be stitched and the mouth allowed to close. The ant’s body was then pinched away, leaving the head holding
the wound together.
2. Several African cultures use poultices made from ground grasshoppers as pain relievers
for migraines. Neurologists hypothesize that grasshopper toxins stimulate the human central nervous system, and dilate blood vessels, increasing circulation. Powdered, sun-dried, grasshopper is turned into a tea for the treatment of asthma and hepatitis.
3. Across Southeast Asia, healers have capitalized on blister beetles’ healing powers since ancient times. Also known as “Spanish Fly,” the beetles represent humankind’s first remedy for erectile dysfunction. Blister beetle secretions reduce burning pain sensations commonly associated with urinary tract infections, insect bites, kidney problems, and burns.
Blister beetles secrete cantharidin, which is effective in treating severe viral infections,
because it prevents viral cell reproduction, and may be useful in treatment of cancerous
tumours resistant to radiation and chemotherapy. A number of research papers have been published confirming that cantharidin has multiple effects on cancer cells.
4. Emerging science suggests that silkworm extracts may have benefits, as dietary
supplements, for patients with heart disease and circulatory disorders. Preliminary studies indicate they reduce serum cholesterol, and dissolve vascular plaque. Boiled silkworm pupae  have been used by Chinese medicine to treat apoplexy, bronchitis, convulsions and frequent urination. A bacteria that lives in the digestive system of silkworms contains a substance known as serrapeptase. This substance appears to offer pain relief for people with back injuries. There are studies underway to see if they can also help with sports injuries.
5. Traditional Asian practitioners use centipedes to treat tetanus, seizures, and convulsions. Centipedes are dried, ground into a paste, and applied topically to sores and carbuncles.  
6. Ayurveda uses termites, and their mounds, for ulcers, rheumatic diseases, anaemia, and
pain. In Africa Termites are used in asthma, bronchitis, influenza, whooping cough.
7. Spider silk is an ideal material to use in skin grafts, or ligament implants, because it is
one of the strongest known natural fibres, and triggers little immune response. Spider silk
may also be used to make fine sutures for stitching nerves, or eyes, to heal with little
scarring.
8. The Jatropha Leaf Miner, a moth who feeds on the Jatropha plant, is an example of an
insect considered a pest who has medicinal value. The larvae of the insect are harvested,
boiled, and mashed into a paste which is administered topically and is said to induce
lactation, reduce fever, and soothe gastrointestinal tracts.
9. In southwestern Nigeria, an infected foot is treated by smearing and rubbing mashed
mole crickets on it.
10. Locusts are eaten in post childbirth anaemia, lung diseases, asthma and chronic cough.
11. The May Beetle is used as a remedy for anaemia and rheumatism. The Peanut Beetle for asthma, arthritis, tuberculosis and the Palm Beetle for earache.
12. Cicadas are crushed and applied to migraine headaches and ear infection.
13. The Red Velvet Mite is eaten in urogenital disorders, and paralysis. 
14. A mass of boiled Mealybugs was ingested to alleviate the affects of poisonous
mushrooms and other fungi, or diarrhoea, and to clean the teeth and in the treatment of
caries.
15. In the heads of cockroaches are chemical compounds that can kill Escherichia coli
(E. Coli) and Methicillin-resistant Staphylococcus aureus (MRSA), two harmful bacteria
that are resistant to most drugs. It was discovered that tissues, taken from the brains and nervous system of the insects, killed off over 90% of MRSA infections and E. coli.
16. Scientists from the Institute for Biomedical Research, Barcelona, have carried out successful in vitro tests, using wasp venom, to kill cancer cells. Wasp venom contains
Polybia MPI (from venom of the wasp Polybiapaulista), which shows anti tumour activity
and kills only cancer cells, leaving the healthy cells around it.
17. Studies on caterpillar venom show that cecropins, which are a group of peptides isolated from the caterpillar blood of the Giant Silk Moth Hyalophoracecropia, have anti-microbial activity, and have been used as a potent anti-cancer agent against a variety of tumour cell
lines. Cecropins are active against several mammalian lymphomas and leukaemia, and may offer novel strategies for the treatment of bladder cancer.
18. In 1993 Margatoxin was synthesized from the venom of the Central American bark scorpion. Patented by Merck, it has the potential to prevent bypass graft failure. Scorpion venom extract has been shown to be able to detect and spotlight cancer cells, under a
special light used during surgery.
All these insects are being killed in the millions everyday as pests. Unless we take action to protect and develop our environment sustainably, and get rid of pesticides/herbicides and poisons that kill them and us, the window of chance for the discovery of new medicinal
agents will be closed forever. One day we will find that the millions of insects we have
killed, through pest control, could have saved our lives. By then it might be too late for
them and us.
Photo Credit : Shutterstock
Twitter: @ManekaGandhiBJP